The Committee on Energy and Commerce has broad jurisdiction over energy policy, healthcare, telecommunications, consumer protection, environmental quality, and interstate and foreign commerce. It oversees numerous federal agencies and shapes legislation impacting significant sectors of the economy.

The Committee on Science, Space, and Technology has jurisdiction over non-defense federal scientific research and development, including programs at NASA, the National Science Foundation, and the Department of Energy. It covers areas like space exploration, energy research, environmental science, and technology innovation.