H.R. 3029: To amend the Research and Development, Competition, and Innovation Act to support nucleic acid screening, and for other purposes.

Introduced Apr 28, 20253 cosponsors

Sponsor

Andrea Salinas

Andrea Salinas

Democrat · OR-6

Dangerous DNA orders should be caught before they ship

4 min readLast updated September 28, 2026

Why it matters

Anyone with a lab account can order a custom strand of DNA or RNA, and whether a vendor spots a dangerous sequence depends on the screening tool it happens to use. H.R. 3029 puts $25 million over five years behind federal testing and standards so those screens can be measured, compared, and trusted, with AI-assisted designs explicitly in scope.

Synthetic DNA and RNA are everyday research supplies. Vendors print custom sequences for vaccine work, diagnostics, and basic biology, and many run each order against lists of sequences tied to dangerous organisms before filling it.

H.R. 3029 would make the National Institute of Standards and Technology responsible for testing whether those screens actually catch what they are supposed to catch. NIST already sets measurement standards for everything from timekeeping to cybersecurity. This bill adds nucleic acid screening to that list.

The work covers five areas: testing screening accuracy and reliability, securing the databases of flagged sequences, practical guidance for running screens, conformity assessment so a tool can be checked against a standard, and methods for judging whether any of it is working.

The bill also adds risks tied to artificial intelligence to NIST's existing standards work on engineering biology and biomanufacturing. AI design tools can generate sequences that do not match anything on a known list, which is the gap a standards body would need to account for.

NIST would not write these rules alone. It must convene a consortium of vendors, universities, nonprofits, and customers to set shared priorities and research roadmaps, and report the group's findings to Congress within 18 months of its first meeting.

Nothing in the bill creates a penalty, a ban, or a mandate on vendors — it builds the yardstick, not the enforcement. The authorization is $5 million a year from fiscal 2027 through 2031.

Bill Progress

IntroducedApr 28
Committee 
Pass HouseJul 20
Pass Senate 
Signed 
Law 

Latest Action · Jul 21, 2026

1/3

Passed the House, received in Senate

H.R. 3029 Bill Summary

What H.R. 3029 actually does.

1

Screening tools get tested against a real standard

NIST would run measurement research to improve the accuracy, efficacy, and reliability of screening for synthetic DNA and RNA orders, and develop conformity-assessment practices so a screening tool can be checked against a standard.

2

AI-designed sequences come into scope

The bill adds risks associated with artificial intelligence to NIST's standards work on engineering biology and biomanufacturing risk management.

3

Lists of dangerous sequences get secured

NIST would develop best practices for operational security, access controls, and management of the sequence-of-concern databases that screening depends on.

4

Vendors get implementation guidance

NIST would produce technical guidance on running screening so it is both effective and secure, plus methods to measure whether that guidance is working once adopted.

5

Industry, universities, and buyers shape the rules together

NIST must convene a consortium including industry, higher education, nonprofits, and customers to develop and periodically update consensus best practices for screening synthetic nucleic acid purchases, and to set research roadmaps.

6

Congress gets findings within 18 months

NIST must report the consortium's findings to the Senate Commerce Committee and the House Science Committee no later than 18 months after the consortium first meets.

Who benefits from H.R. 3029?

Companies that synthesize DNA and RNA

Vendors would be able to test their screening against a federal benchmark and point to that result, rather than each defending a homegrown approach.

Researchers who order synthetic sequences

If you run a university or biotech lab, common standards could mean fewer unexplained holds on legitimate orders and clearer expectations about what gets flagged and why.

Public health and biodefense agencies

Agencies watching for dangerous biological material would gain a measurable way to judge whether the commercial supply chain is catching risky orders.

Everyone downstream of a biosecurity failure

The bill's premise is that a synthesized pathogen sequence is easier to stop at the order form than after it ships. Better screening is a protection most people never see.

Who is affected by H.R. 3029?

NIST

NIST takes on the research, the consortium, and the report to Congress, funded at $5 million a year if appropriators provide the money.

Synthetic nucleic acid vendors

The bill imposes no requirements on vendors, but once NIST standards exist, customers, funders, or future legislation could expect vendors to meet them.

Universities, nonprofits, and customers in the consortium

Participants would spend time helping write consensus priorities and best practices for procurement screening.

House and Senate science committees

The Senate Commerce Committee and House Science Committee receive the consortium report and would decide whether stronger measures are needed.

Cost & Funding

Authorization

$5,000,000 per year for fiscal 2027 through 2031

  • Five years at $5 million comes to $25 million total.
  • The money comes out of amounts already authorized for NIST's scientific and technical research and services laboratory activities under the underlying law, so it is set aside within NIST's lab budget rather than added on top.
  • An authorization is a ceiling, not a check. Appropriators still have to provide the funds each year.
  • The bill creates no fees, fines, or grant programs.
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On the Record

What Congress Is Saying

H.R. 3029 has come up 9 times in the Congressional Record so far.

H.R. 3029 also appeared in 1 more House floor reference and 3 routine cosponsor filings.

HR3029 Legislative Journey

5 actions

Committee Action

Jul 21, 2026

Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation.

House: Vote Held

Jul 20, 2026

On motion to suspend the rules and pass the bill, as amended Agreed to by voice vote. (text: CR H4666)

House: Committee Action

Jul 16, 2026

119-751

Reported by the Committee on Science, Space, and Technology. H. Rept. 119-751.

House: Vote Held

Apr 29, 2025

Ordered to be Reported by Voice Vote.

House: Committee Action

Apr 28, 2025

Referred to the House Committee on Science, Space, and Technology.

About the Sponsor

Andrea Salinas

Andrea Salinas

Democrat, Oregon's 6th congressional district · 3 years in Congress

Committees: Science, Space, and Technology, Agriculture

View full profile →

Cosponsors (3)

No new cosponsors in 533 days — momentum stalled

This bill has 3 cosponsors: 2 Democrats, 1 Republican, reflecting bipartisan support. Cosponsors represent 3 states: Delaware, Georgia, New York.

2Democrats1Republican·3 statesBipartisan

Committee Sponsors

Commerce, Science, and Transportation Committee

13D15R
|0 signed28 not yet

0 of 28 committee members cosponsored

No committee members have cosponsored this bill

Science, Space, and Technology Committee

18D22R
|3 signed37 not yet

3 of 40 committee members cosponsored

29 Democrats across these committees haven't cosponsored yet. Mobilize their constituents

H.R. 3029 Quick Facts

Cosponsors
3
Richard McCormick
Sarah McBride
Josh Riley
Committee
Commerce, Science, and Transportation
Chamber
House
Policy
Science, Technology, Communications
Introduced
Apr 28, 2025

Passed the House, received in Senate

Jul 21, 2026

Constituent Resources

Get notified when this bill moves

Official Sources

H.R. 3029 on Congress.gov

Official bill page with the full text, House passage record, and Senate committee referral for H.R. 3029.

NIST Biosecurity for Synthetic Nucleic Acid Sequences

NIST project already building benchmark datasets for DNA synthesis screening tools and studying how AI-designed sequences can slip past them, the work this bill would expand and fund.

HHS Screening Framework Guidance for Synthetic Nucleic Acids

The current federal guidance on screening synthetic DNA and RNA orders, setting the voluntary baseline that NIST standards would help vendors measure against.

CBO Cost Estimate for H.R. 3029

CBO scored an earlier version of the bill at $5 million a year, about $25 million total, assuming the money is appropriated.

42 U.S.C. 18931: Engineering Biology and Biometrology

The existing NIST engineering biology and biomanufacturing authority that H.R. 3029 amends to add nucleic acid screening and AI-related risks.

NIST Biosystems and Biomaterials Division

The NIST laboratory division that runs engineering biology measurement research and industry consortia.

Public Law 117-167 on GovInfo

Official text of the CHIPS and Science Act, which created the NIST engineering biology section this bill amends.

H.R. 3029 Common Questions

What does H.R. 3029 do?

It directs NIST, the federal standards lab, to research and set standards for screening synthetic DNA and RNA orders, so vendors can test whether their checks actually catch dangerous sequences.

What is DNA synthesis screening?

When a lab orders a custom DNA or RNA sequence, the vendor can compare it against lists of sequences linked to dangerous pathogens or toxins before making it. Screening is that check. H.R. 3029 focuses on making it accurate and consistent.

Has H.R. 3029 passed?

It passed the House by voice vote on July 20, 2026. It is now with the Senate Commerce, Science, and Transportation Committee and needs Senate passage and a signature to become law.

How much does H.R. 3029 cost?

It authorizes $5 million a year for fiscal 2027 through 2031, $25 million total, drawn from NIST's existing lab research authorization. Congress still has to appropriate the money each year.

What does artificial intelligence have to do with this bill?

AI tools can help design biological sequences. The bill adds AI-related risks to NIST's standards work on engineering biology, so screening guidance accounts for them. It does not regulate AI models themselves.

Would DNA vendors be required to screen orders?

Not under this bill. H.R. 3029 creates no mandate, penalty, or ban. It funds research, guidance, and standards that vendors and buyers could adopt.

What is a sequence-of-concern database?

It's the reference list screening software checks orders against — sequences tied to dangerous organisms or toxins. The bill asks NIST to set best practices for securing and controlling access to these lists.

Who helps NIST write the screening standards?

A consortium NIST must convene, including DNA synthesis companies, universities, nonprofits, and customers. NIST reports the group's findings to Congress within 18 months of its first meeting.

Based on H.R. 3029 bill text

H.R. 3029 Bill Text

PDF

“To amend the Research and Development, Competition, and Innovation Act to support nucleic acid screening, and for other purposes.”

Source: U.S. Government Publishing Office

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