The Committee on Agriculture, Nutrition, and Forestry oversees America's agricultural industry, including research, production, marketing, and price stabilization for commodities. It also holds jurisdiction over national nutrition programs like SNAP and school meals, forestry, rural development, and related areas.

The Committee on Foreign Relations leads Senate consideration of U.S. foreign policy, including treaties, diplomatic nominations, foreign aid, and arms control. It shapes legislation concerning international relations and provides oversight of the State Department and other foreign affairs agencies.

The Committee on the Judiciary conducts oversight of the Department of Justice and considers nominations for federal judgeships, including the Supreme Court. Its legislative jurisdiction covers constitutional amendments, federal criminal law, immigration, antitrust, patents, and civil liberties.

The Committee on Small Business and Entrepreneurship focuses on issues affecting small businesses, including access to capital, federal procurement opportunities, and regulatory burdens. It provides oversight of the Small Business Administration (SBA) and develops legislation aimed at fostering entrepreneurship.