The Committee on Armed Services exercises legislative oversight for the nation's military, including the Department of Defense, military research and development, nuclear energy activities, and benefits for members of the armed forces. It also handles the confirmation of presidential nominees for senior defense and military positions.

The Committee on Homeland Security and Governmental Affairs provides oversight of homeland security operations and the efficiency and management of the federal government. Its jurisdiction includes counterterrorism, cybersecurity, border security, emergency management, and governmental affairs, including the Postal Service and the Census Bureau.

The Committee on the Judiciary conducts oversight of the Department of Justice and considers nominations for federal judgeships, including the Supreme Court. Its legislative jurisdiction covers constitutional amendments, federal criminal law, immigration, antitrust, patents, and civil liberties.

The United States Senate Caucus on International Narcotics Control oversees and promotes international cooperation against drug trafficking and abuse. It monitors U.S. counternarcotics policies and programs abroad, working with foreign governments and international bodies.

The Committee on Veterans' Affairs handles legislation related to veterans' benefits, healthcare, housing, employment, and memorials. It provides oversight for the Department of Veterans Affairs (VA) and addresses issues affecting former service members.