The Committee on Armed Services exercises legislative oversight for the nation's military, including the Department of Defense, military research and development, nuclear energy activities, and benefits for members of the armed forces. It also handles the confirmation of presidential nominees for senior defense and military positions.

The Committee on Banking, Housing, and Urban Affairs oversees legislation related to banks, financial institutions, housing, urban development, and economic policy. Its jurisdiction includes monetary policy, financial stability, consumer protection in financial services, securities markets, and international finance.

The Committee on Health, Education, Labor, and Pensions (HELP) oversees matters relating to public health, education, labor standards, employment, and retirement security. It addresses issues ranging from biomedical research and food/drug safety to K-12 education, workplace safety, and private pension plans.

The Committee on Veterans' Affairs handles legislation related to veterans' benefits, healthcare, housing, employment, and memorials. It provides oversight for the Department of Veterans Affairs (VA) and addresses issues affecting former service members.