The Committee on Armed Services exercises legislative oversight for the nation's military, including the Department of Defense, military research and development, nuclear energy activities, and benefits for members of the armed forces. It also handles the confirmation of presidential nominees for senior defense and military positions.

The Committee on Energy and Natural Resources handles matters related to energy development, conservation, regulation, nuclear energy, national parks, public lands, and natural resource management. It oversees the Department of Energy and the Department of the Interior.

The Committee on the Judiciary conducts oversight of the Department of Justice and considers nominations for federal judgeships, including the Supreme Court. Its legislative jurisdiction covers constitutional amendments, federal criminal law, immigration, antitrust, patents, and civil liberties.

The Committee on Small Business and Entrepreneurship focuses on issues affecting small businesses, including access to capital, federal procurement opportunities, and regulatory burdens. It provides oversight of the Small Business Administration (SBA) and develops legislation aimed at fostering entrepreneurship.

The Committee on Veterans' Affairs handles legislation related to veterans' benefits, healthcare, housing, employment, and memorials. It provides oversight for the Department of Veterans Affairs (VA) and addresses issues affecting former service members.