The Committee on Armed Services exercises legislative oversight for the nation's military, including the Department of Defense, military research and development, nuclear energy activities, and benefits for members of the armed forces. It also handles the confirmation of presidential nominees for senior defense and military positions.

The Committee on Commerce, Science, and Transportation addresses a wide range of issues including interstate commerce, transportation systems, science and technology policy, space exploration, and consumer protection. It oversees agencies like the Department of Transportation, NASA, the FCC, and the FTC.

The Committee on Environment and Public Works deals with legislation concerning environmental protection, infrastructure projects like highways and water systems, and disaster response. Its jurisdiction includes oversight of the Environmental Protection Agency and the Army Corps of Engineers.

The Committee on Veterans' Affairs handles legislation related to veterans' benefits, healthcare, housing, employment, and memorials. It provides oversight for the Department of Veterans Affairs (VA) and addresses issues affecting former service members.